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Registros recuperados: 16 | |
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Pizzetti, Ilaria; Gobet, Angelique; Fuchs, Bernhard M.; Amann, Rudolf; Fazi, Stefano. |
The phylum Planctomycetes is involved in important processes, such as the mineralization of algal biomass and the removal of nitrogen. Using a combination of 16S rRNA sequence analysis and in situ hybridization, we analyzed the diversity and dynamics of Planctomycetes in a shallow meso-eutrophic lake, Lago di Paola, Italy. Planctomycetes detected by the probe PLA46 accounted for 1 to 5% of prokaryotic picoplankton. Abundances were higher in the coastal lake than in the adjacent marine waters. In the surface waters of the lake, the numbers of Planctomycetes fluctuated greatly, reaching a maximum of 1.5 x 10(6) cells ml(-1) in July. The hypoxic bottom waters had less variable cell abundances. The Planctomycetes counts were positively correlated with... |
Tipo: Text |
Palavras-chave: Coastal lake ecology; Planctomycetes; Bacterial diversity; FISH; CARD-FISH; 16S rRNA gene sequencing. |
Ano: 2011 |
URL: https://archimer.ifremer.fr/doc/00488/59948/63196.pdf |
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Brunet, Maéva; De Bettignies, Florian; Le Duff, Nolwen; Tanguy, Gwenn; Davoult, Dominique; Leblanc, Catherine; Gobet, Angelique; Thomas, François. |
Kelps are dominant primary producers in temperate coastal ecosystems. Large amounts of kelp biomass can be exported to the seafloor during the algal growth cycle or following storms, creating new ecological niches for the associated microbiota. Here, we investigated the bacterial community associated with the kelp Laminaria hyperborea during its accumulation and degradation on the seafloor. Kelp tissue, seawater and sediment were sampled during a six‐month in situ experiment simulating kelp detritus accumulation. Evaluation of the epiphytic bacterial community abundance, structure, taxonomic composition and predicted functional profiles evidenced a biphasic succession. Initially dominant genera (Hellea, Litorimonas, Granulosicoccus) showed a rapid and... |
Tipo: Text |
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Ano: 2021 |
URL: https://archimer.ifremer.fr/doc/00666/77808/79983.pdf |
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Jouault, Albane; Gobet, Angelique; Simon, Marjolaine; Portier, Emilie; Perennou, Morgan; Corre, Erwan; Gaillard, Fanny; Vallenet, David; Michel, Gurvan; Fleury, Yannick; Bazire, Alexis; Dufour, Alain. |
The aim was to identify and study the antibiofilm protein secreted by the marine bacterium Pseudoalteromonas sp. 3J6. The latter is active against marine and terrestrial bacteria, including Pseudomonas aeruginosa clinical strains forming different biofilm types. Several amino acid sequences were obtained from the partially purified antibiofilm protein, named alterocin. The Pseudoalteromonas sp. 3J6 genome was sequenced and a candidate alt gene was identified by comparing the genome-encoded proteins to the sequences from purified alterocin. Expressing the alt gene in another non-active Pseudoalteromonas sp. strain, 3J3, demonstrated that it is responsible for the antibiofilm activity. Alterocin is a 139-residue protein including a predicted 20-residue... |
Tipo: Text |
Palavras-chave: Antibiofilm protein; Pseudoalteromonas; Pseudomonas aeruginosa; Biofilm. |
Ano: 2020 |
URL: https://archimer.ifremer.fr/doc/00643/75517/76405.pdf |
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Forster, Dominik; Dunthorn, Micah; Mahe, Frederic; Dolan, John R.; Audic, Stephane; Bass, David; Bittner, Lucie; Boutte, Christophe; Christen, Richard; Claverie, Jean-michel; Decelle, Johan; Edvardsen, Bente; Egge, Elianne; Eikrem, Wenche; Gobet, Angelique; Kooistra, Wiebe H. C. F.; Logares, Ramiro; Massana, Ramon; Montresor, Marina; Not, Fabrice; Ogata, Hiroyuki; Pawlowski, Jan; Pernice, Massimo C.; Romac, Sarah; Shalchian-tabrizi, Kamran; Simon, Nathalie; Richards, Thomas A.; Santini, Sebastien; Sarno, Diana; Siano, Raffaele; Vaulot, Daniel; Wincker, Patrick; Zingone, Adriana; De Vargas, Colomban; Stoeck, Thorsten. |
Marine protist diversity inventories have largely focused on planktonic environments, while benthic protists have received relatively little attention. We therefore hypothesize that current diversity surveys have only skimmed the surface of protist diversity in marine sediments, which may harbour greater diversity than planktonic environments. We tested this by analyzing sequences of the hypervariable V4 18S rRNA from benthic and planktonic protist communities sampled in European coastal regions. Despite a similar number of OTUs in both realms, richness estimations indicated that we recovered at least 70% of the diversity in planktonic protist communities, but only 33% in benthic communities. There was also little overlap of OTUs between planktonic and... |
Tipo: Text |
Palavras-chave: Benthic microbial communities; Coastal environments; Protist diversity; High-throughput sequencing. |
Ano: 2016 |
URL: https://archimer.ifremer.fr/doc/00341/45233/44658.pdf |
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Gobet, Angelique; Boeer, Simone I.; Huse, Susan M.; Van Beusekom, Justus E. E.; Quince, Christopher; Sogin, Mitchell L.; Boetius, Antje; Ramette, Alban. |
Coastal sands filter and accumulate organic and inorganic materials from the terrestrial and marine environment, and thus provide a high diversity of microbial niches. Sands of temperate climate zones represent a temporally and spatially highly dynamic marine environment characterized by strong physical mixing and seasonal variation. Yet little is known about the temporal fluctuations of resident and rare members of bacterial communities in this environment. By combining community fingerprinting via pyrosequencing of ribosomal genes with the characterization of multiple environmental parameters, we disentangled the effects of seasonality, environmental heterogeneity, sediment depth and biogeochemical gradients on the fluctuations of bacterial communities... |
Tipo: Text |
Palavras-chave: 454 pyrosequencing; Coastal seas; Bacterial diversity; Multivariate analysis; Rare biosphere. |
Ano: 2012 |
URL: https://archimer.ifremer.fr/doc/00488/59947/63192.pdf |
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Gobet, Angelique; Boetius, Antje; Ramette, Alban. |
Changes in richness and bacterial community structure obtained via 454 Massively Parallel Tag Sequencing (MPTS) and Automated Ribosomal Intergenic Analysis (ARISA) were systematically compared to determine whether and how the ecological knowledge obtained from both molecular techniques could be combined. We evaluated community changes over time and depth in marine coastal sands at different levels of taxonomic resolutions, sequence corrections and sequence abundances. Although richness over depth layers or sampling dates greatly varied [approximate to 30% and 70-80% new operational taxonomic units (OTU) between two samples with ARISA and MPTS respectively], overall patterns of community variations were similar with both approaches. Alpha-diversity... |
Tipo: Text |
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Ano: 2014 |
URL: https://archimer.ifremer.fr/doc/00488/59943/63180.pdf |
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Gobet, Angelique; Barbeyron, Tristan; Matard-mann, Maria; Magdelenat, Ghislaine; Vallenet, David; Duchaud, Eric; Michel, Gurvan. |
About half of seaweed biomass is composed of polysaccharides. Most of these complex polymers have a marked polyanionic character. For instance, the red algal cell wall is mainly composed of sulfated galactans, agars and carrageenans, while brown algae contain alginate and fucose-containing sulfated polysaccharides (FCSP) as cell wall polysaccharides. Some marine heterotrophic bacteria have developed abilities to grow on such macroalgal polysaccharides. This is the case of Pseudoalteromonas carrageenovora 9(T) (ATCC 43555(T)), a marine gammaproteobacterium isolated in 1955 and which was an early model organism for studying carrageenan catabolism. We present here the genomic analysis of P. carrageenovora. Its genome is composed of two chromosomes and of a... |
Tipo: Text |
Palavras-chave: Carrageenan; CAZymes; Alginate; Gammaproteobacteria; Pseudoalteromonas; Marine bacteria; Algal holobiont; Biofilm. |
Ano: 2018 |
URL: https://archimer.ifremer.fr/doc/00489/60070/63377.pdf |
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Dittami, Simon M.; Barbeyron, Tristan; Boyen, Catherine; Cambefort, Jeanne; Collet, Guillaume; Delage, Ludovic; Gobet, Angelique; Groisillier, Agnes; Leblanc, Catherine; Michel, Gurvan; Scornet, Delphine; Siegel, Anne; Tapia, Javier E.; Tonon, Thierry. |
Rhizobiales and related orders of Alphaproteobacteria comprise several genera of nodule-inducing symbiotic bacteria associated with plant roots. Here we describe the genome and the metabolic network of "Candidatus Phaeomarinobacter ectocarpi" Ec32, a member of a new candidate genus closely related to Rhizobiales and found in association with cultures of the filamentous brown algal model Ectocarpus. The "Ca. P. ectocarpi" genome encodes numerous metabolic pathways that may be relevant for this bacterium to interact with algae. Notably, it possesses a large set of glycoside hydrolases and transporters, which may serve to process and assimilate algal metabolites. It also harbors several proteins likely to be involved in the synthesis of algal hormones such as... |
Tipo: Text |
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Ano: 2014 |
URL: https://archimer.ifremer.fr/doc/00488/59944/63183.pdf |
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Brown, Peter; Tan, Aik-choon; El-esawi, Mohamed A.; Liehr, Thomas; Blanck, Oliver; Gladue, Douglas P.; Almeida, Gabriel M. F.; Cernava, Tomislav; Sorzano, Carlos O.; Yeung, Andy W. K.; Engel, Michael S.; Chandrasekaran, Arun Richard; Muth, Thilo; Staege, Martin S.; Daulatabad, Swapna V.; Widera, Darius; Zhang, Junpeng; Meule, Adrian; Honjo, Ken; Pourret, Olivier; Yin, Cong-cong; Zhang, Zhongheng; Cascella, Marco; Flegel, Willy A.; Goodyear, Carl S.; Van Raaij, Mark J.; Bukowy-bieryllo, Zuzanna; Campana, Luca G.; Kurniawan, Nicholas A.; Lalaouna, David; Huttner, Felix J.; Ammerman, Brooke A.; Ehret, Felix; Cobine, Paul A.; Tan, Ene-choo; Han, Hyemin; Xia, Wenfeng; Mccrum, Christopher; Dings, Ruud P. M.; Marinello, Francesco; Nilsson, Henrik; Nixon, Brett; Voskarides, Konstantinos; Yang, Long; Costa, Vincent D.; Bengtsson-palme, Johan; Bradshaw, William; Grimm, Dominik G.; Kumar, Nitin; Martis, Elvis; Prieto, Daniel; Sabnis, Sandeep C.; Amer, Said E. D. R.; Liew, Alan W. C.; Perco, Paul; Rahimi, Farid; Riva, Giuseppe; Zhang, Chongxing; Devkota, Hari P.; Ogami, Koichi; Basharat, Zarrin; Fierz, Walter; Siebers, Robert; Tan, Kok-hian; Boehme, Karen A.; Brenneisen, Peter; Brown, James A. L.; Dalrymple, Brian P.; Harvey, David J.; Ng, Grace; Werten, Sebastiaan; Bleackley, Mark; Dai, Zhanwu; Dhariwal, Raman; Gelfer, Yael; Hartmann, Marcus D.; Miotla, Pawel; Tamaian, Radu; Govender, Pragashnie; Gurney-champion, Oliver J.; Kauppila, Joonas H.; Zhang, Xiaolei; Echeverria, Natalia; Subhash, Santhilal; Sallmon, Hannes; Tofani, Marco; Bae, Taeok; Bosch, Oliver; Cuiv, Paraic O.; Danchin, Antoine; Diouf, Barthelemy; Eerola, Tuomas; Evangelou, Evangelos; Filipp, Fabian V.; Klump, Hannes; Kurgan, Lukasz; Smith, Simon S.; Terrier, Olivier; Tuttle, Neil; Ascher, David B.; Janga, Sarath C.; Schulte, Leon N.; Becker, Daniel; Browngardt, Christopher; Bush, Stephen J.; Gaullier, Guillaume; Ide, Kazuki; Meseko, Clement; Werner, Gijsbert D. A.; Zaucha, Jan; Al-farha, Abd A.; Greenwald, Noah F.; Popoola, Segun I.; Rahman, Md Shaifur; Xu, Jialin; Yang, Sunny Y.; Hiroi, Noboru; Alper, Ozgul M.; Baker, Chris I.; Bitzer, Michael; Chacko, George; Debrabant, Birgit; Dixon, Ray; Forano, Evelyne; Gilliham, Matthew; Kelly, Sarah; Klempnauer, Karl-heinz; Lidbury, Brett A.; Lin, Michael Z.; Lynch, Iseult; Ma, Wujun; Maibach, Edward W.; Mather, Diane E.; Nandakumar, Kutty S.; Ohgami, Robert S.; Parchi, Piero; Tressoldi, Patrizio; Xue, Yu; Armitage, Charles; Barraud, Pierre; Chatzitheochari, Stella; Coelho, Luis P.; Diao, Jiajie; Doxey, Andrew C.; Gobet, Angelique; Hu, Pingzhao; Kaiser, Stefan; Mitchell, Kate M.; Salama, Mohamed F.; Shabalin, Ivan G.; Song, Haijun; Stevanovic, Dejan; Yadollahpour, Ali; Zeng, Erliang; Zinke, Katharina; Alimba, C. G.; Beyene, Tariku J.; Cao, Zehong; Chan, Sherwin S.; Gatchell, Michael; Kleppe, Andreas; Piotrowski, Marcin; Torga, Gonzalo; Woldesemayat, Adugna A.; Cosacak, Mehmet I.; Haston, Scott; Ross, Stephanie A.; Williams, Richard; Wong, Alvin; Abramowitz, Matthew K.; Effiong, Andem; Lee, Senhong; Abid, Muhammad Bilal; Agarabi, Cyrus; Alaux, Cedric; Albrecht, Dirk R.; Atkins, Gerald J.; Beck, Charles R.; Bonvin, A. M. J. J.; Bourke, Emer; Brand, Thomas; Braun, Ralf J.; Bull, James A.; Cardoso, Pedro; Carter, Dee; Delahay, Robin M.; Ducommun, Bernard; Duijf, Pascal H. G.; Epp, Trevor; Eskelinen, Eeva-liisa; Fallah, Mazyar; Farber, Debora B.; Fernandez-triana, Jose; Feyerabend, Frank; Florio, Tullio; Friebe, Michael; Furuta, Saori; Gabrielsen, Mads; Gruber, Jens; Grybos, Malgorzata; Han, Qian; Heinrich, Michael; Helantera, Heikki; Huber, Michael; Jeltsch, Albert; Jiang, Fan; Josse, Claire; Jurman, Giuseppe; Kamiya, Haruyuki; De Keersmaecker, Kim; Kristiansson, Erik; De Leeuw, Frank-erik; Li, Jiuyong; Liang, Shide; Lopez-escamez, Jose A.; Lopez-ruiz, Francisco J.; Marchbank, Kevin J.; Marschalek, Rolf; Martin, Carmen S.; Miele, Adriana E.; Montagutelli, Xavier; Morcillo, Esteban; Nicoletti, Rosario; Niehof, Monika; O'Toole, Ronan; Ohtomo, Toshihiko; Oster, Henrik; Palma, Jose-alberto; Paterson, Russell; Peifer, Mark; Portilla, Maribel; Portillo, M. C.; Pritchard, Antonia L.; Pusch, Stefan; Raghava, Gajendra P. S.; Roberts, Nicola J.; Ross, Kehinde; Schuele, Birgitt; Sergeant, Kjell; Shen, Jun; Stella, Alessandro; Sukocheva, Olga; Uversky, Vladimir N.; Vanneste, Sven; Villet, Martin H.; Viveiros, Miguel; Vorholt, Julia A.; Weinstock, Christof; Yamato, Masayuki; Zabetakis, Ioannis; Zhao, Xin; Ziegler, Andreas; Aizat, Wan M.; Atlas, Lauren; Bridges, Kristina M.; Chakraborty, Sayan; Deschodt, Mieke; Domingues, Helena S.; Esfahlani, Shabnam S.; Falk, Sebastian; Guisado, J. L.; Kane, Nolan C.; Kueberuwa, Gray; Lau, Colleen L.; Liang, Dai; Liu, Enwu; Luu, Andreas M.; Ma, Chuang; Ma, Lisong; Moyer, Robert; Norris, Adam D.; Panthee, Suresh; Parsons, Jerod R.; Peng, Yousong; Pinto, Ines Mendes; Reschke, Cristina R.; Sillanpaa, Elina; Stewart, Christopher J.; Uhle, Florian; Yang, Hui; Zhou, Kai; Zhu, Shu; Ashry, Mohamed; Bergsland, Niels; Berthold, Maximilian; Chen, Chang-er; Colella, Vito; Cuypers, Maarten; Eskew, Evan A.; Fan, Xiao; Gajda, Maksymilian; Gonzalezlez-prendes, Rayner; Goodin, Amie; Graham, Emily B.; Groen, Ewout J. N.; Gutierrez-sacristan, Alba; Habes, Mohamad; Heffler, Enrico; Higginbottom, Daniel B.; Janzen, Thijs; Jayaraman, Jayakumar; Jibb, Lindsay A.; Jongen, Stefan; Kinyanjui, Timothy; Koleva-kolarova, Rositsa G.; Li, Zhixiu; Liu, Yu-peng; Lund, Bjarte A.; Lussier, Alexandre A.; Ma, Liping; Mier, Pablo; Moore, Matthew D.; Nagler, Katja; Orme, Mark W.; Pearson, James A.; Prajapati, Anilkumar S.; Saito, Yu; Troder, Simon E.; Uchendu, Florence; Verloh, Niklas; Voutchkova, Denitza D.; Abu-zaid, Ahmed; Bakkach, Joaira; Baumert, Philipp; Dono, Marcos; Hanson, Jack; Herbelet, Sandrine; Hobbs, Emma; Kulkarni, Ameya; Kumar, Narendra; Liu, Siqi; Loft, Nikolai D.; Reddan, Tristan; Senghore, Thomas; Vindin, Howard; Xu, Haotian; Bannon, Ross; Chen, Branson; Cheung, Johnny T. K.; Cooper, Jeffrey; Esnakul, Ashwini K.; Feghali, Karine A.; Ghelardi, Emilia; Gnasso, Agostino; Horbar, Jeffrey; Lai, Hei M.; Li, Jian; Ma, Lan; Ma, Ruiyan; Pan, Zihang; Peres, Marco A.; Pranata, Raymond; Seow, Esmond; Sydes, Matthew; Testoni, Ines; Westermair, Anna L.; Yang, Yongliang; Afnan, Masoud; Albiol, Joan; Albuquerque, Lucia G.; Amiya, Eisuke; Amorim, Rogerio M.; An, Qianli; Andersen, Stig U.; Aplin, John D.; Argyropoulos, Christos; Asmann, Yan W.; Assaeed, Abdulaziz M.; Atanasov, Atanas G.; Atchison, David A.; Avery, Simon V.; Avillach, Paul; Baade, Peter D.; Backman, Lars; Badie, Christophe; Baldi, Alfonso; Ball, Elizabeth; Bardot, Olivier; Barnett, Adrian G.; Basner, Mathias; Batra, Jyotsna; Bazanova, O. M.; Beale, Andrew; Beddoe, Travis; Bell, Melanie L.; Berezikov, Eugene; Berners-price, Sue; Bernhardt, Peter; Berry, Edward; Bessa, Theolis B.; Billington, Craig; Birch, John; Blakely, Randy D.; Blaskovich, Mark A. T.; Blum, Robert; Boelaert, Marleen; Bogdanos, Dimitrios; Bosch, Carles; Bourgoin, Thierry; Bouvard, Daniel; Boykin, Laura M.; Bradley, Graeme; Braun, Daniel; Brownlie, Jeremy; Bruhl, Albert; Burt, Austin; Butler, Lisa M.; Byrareddy, Siddappa N.; Byrne, Hugh J.; Cabantous, Stephanie; Calatayud, Sara; Candal, Eva; Carlson, Kimberly; Casillas, Sonia; Castelvetro, Valter; Caswell, Patrick T.; Cavalli, Giacomo; Cerovsky, Vaclav; Chagoyen, Monica; Chen, Chang-shi; Chen, Dong F.; Chen, Hao; Chen, Hui; Chen, Jui-tung; Chen, Yinglong; Cheng, Changxiu; Cheng, Jianlin; Chinapaw, Mai; Chinopoulos, Christos; Cho, William C. S.; Chong, Lillian; Chowdhury, Debashish; Chwalibog, Andre; Ciresi, A.; Cockcroft, Shamshad; Conesa, Ana; Cook, Penny A.; Cooper, David N.; Coqueret, Olivier; Corea, Enoka M.; Costa, Elisio; Coupland, Carol; Crawford, Stephanie Y.; Cruz, Aparecido D.; Cui, Huijuan; Cui, Qiang; Culver, David C.; D'Angiulli, Amedeo; Dahms, Tanya E. S.; Daigle, France; Dalgleish, Raymond; Danielsen, Havard E.; Darras, Sebastien; Davidson, Sean M.; Day, David A.; Degirmenci, Volkan; Demaison, Luc; Devriendt, Koenraad; Ding, Jiandong; Dogan, Yunus; Dong, X. C.; Donner, Claudio F.; Dressick, Walter; Drevon, Christian A.; Duan, Huiling; Ducho, Christian; Dumaz, Nicolas; Dwarakanath, Bilikere S.; Ebell, Mark H.; Eisenhardt, Steffen; Elkum, Naser; Engel, Nadja; Erickson, Timothy B.; Fairhead, Michael; Faville, Marty J.; Fejzo, Marlena S.; Festa, Fernanda; Feteira, Antonio; Flood-page, Patrick; Forsayeth, John; Fox, Simon A.; Franks, Steven J.; Frentiu, Francesca D.; Frilander, Mikko J.; Fu, Xinmiao; Fujita, Satoshi; Galea, Ian; Galluzzi, Luca; Gani, Federica; Ganpule, Arvind P.; Garcia-alix, Antonio; Gedye, Kristene; Giordano, Maurizio; Giunta, Cecilia; Gleeson, Paul A.; Goarant, Cyrille; Gong, Haipeng; Gora, Diop; Gough, Michael J.; Goyal, Ravinder; Graham, Kathryn E.; Grande-perez, Ana; Graves, Patricia M.; Greidanus, Harm; Grice, Darren; Grunau, Christoph; Gumulya, Yosephine; Guo, Yabin; Gurevich, Vsevolod V.; Gusev, Oleg; Hacker, Elke; Hage, Steffen R.; Hagen, Guy; Hahn, Steven; Haller, Dagmar M.; Hammerschmidt, Sven; Han, Jianwei; Han, Renzhi; Handfield, Martin; Hapuarachchi, Hapuarachchige C.; Harder, Timm; Hardingham, Jennifer E.; Heck, Michelle; Heers, Marcel; Hew, Khe F.; Higuchi, Yohei; St Hilaire, Cynthia; Hilton, Rachel; Hodzic, Enisa; Hone, Andrew; Hongoh, Yuichi; Hu, Guoku; Huber, Heinz P.; Hueso, Luis E.; Huirne, Judith; Hurt, Lisa; Idborg, Helena; Ikeo, Kazuho; Ingley, Evan; Jakeman, Philip M.; Jensen, Arne; Jia, Hong; Jia, Husen; Jia, Shuqin; Jiang, Jianping; Jiang, Xingyu; Jin, Yi; Jo, Daehyun; Johnson, Andrew M.; Johnston, Marie; Jonscher, Karen R.; Jorens, Philippe G.; Jorgensen, Jens O. L.; Joubert, Johan W.; Jung, Sin-ho; Junior, Antonio M.; Kahan, Thomas; Kamboj, Sunjeev K.; Kang, Yong-kook; Karamanos, Yannis; Karp, Natasha A.; Kelly, Ryan; Kenna, Ralph; Kennedy, Jonathan; Kersten, Birgit; Khalaf, Roy A.; Khalid, Javaria M.; Khatlani, T.; Khider, Tarig; Kijanka, Gregor S.; King, Sarah R. B.; Kluz, Tomasz; Knox, Paul; Kobayashi, Tatsuya; Koch, Karl-wilhelm; Kohonen-corish, Maija R. J.; Kong, Xiangpeng; Konkle-parker, Deborah; Korpela, Kalevi M.; Kostrikis, Leondios G.; Kraiczy, Peter; Kratz, Harald; Krause, Gunter; Krebsbach, Paul H.; Kristensen, Soren R.; Kumari, Prerna; Kunimatsu, Akira; Kurdak, Hatice; Kwon, Young D.; Lachat, Carl; Lagisz, Malgorzata; Laky, Brenda; Lammerding, Jan; Lange, Matthias; Larrosa, Mar; Laslett, Andrew L.; Leclair, Elizabeth E.; Lee, Kyung-woo; Lee, Ming-yih; Lee, Moon-soo; Li, Genyuan; Li, Jiansheng; Lieb, Klaus; Lim, Yau Y.; Lindsey, Merry L.; Line, Paul-dag; Liu, Dengcai; Liu, Fengbin; Liu, Haiyan; Liu, Hongde; Lloyd, Vett K.; Lo, Te-wen; Locci, Emanuela; Loidl, Josef; Lorenzen, Johan; Lorkowski, Stefan; Lovell, Nigel H.; Lu, Hua; Lu, Wei; Lu, Zhiyong; Luengo, Gustavo S.; Lundh, Lars-gunnar; Lysy, Philippe A.; Mabb, Angela; Mack, Heather G.; Mackey, David A.; Mahdavi, S. R.; Maher, Pamela; Maher, Toby; Maity, Sankar N.; Malgrange, Brigitte; Mamoulakis, Charalampos; Mangoni, Arduino A.; Manke, Thomas; Manstead, Antony S. R.; Mantalaris, Athanasios; Marsal, Jan; Marschall, Hanns-ulrich; Martin, Francis L.; Martinez-raga, Jose; Martinez-salas, Encarnacion; Mathieu, Daniel; Matsui, Yoichi; Maza, Elie; Mccutcheon, James E.; Mckay, Gareth J.; Mcmillan, Brian; Mcmillan, Nigel; Meads, Catherine; Medina, Loreta; Merrick, B. Alex; Metzger, Dennis W.; Meunier, Frederic A.; Michaelis, Martin; Micheau, Olivier; Mihara, Hisaaki; Mintz, Eric M.; Mizukami, Takuo; Moalic, Yann; Mohapatra, D. P.; Monteiro, Antonia; Montes, Matthieu; Moran, John V.; Morozov, Sergey Y.; Mort, Matthew; Murai, Noriyuki; Murphy, Denis J.; Murphy, Susan K.; Murray, Shauna A.; Naganawa, Shinji; Nammi, Srinivas; Nasios, Grigorios; Natoli, Roman M.; Nguyen, Frederique; Nicol, Christine; Van Nieuwerburgh, Filip; Nilsen, Erlend B.; Nobile, Clarissa J.; O'Mahony, Margaret; Ohlsson, Sophie; Olatunbosun, Oluremi; Olofsson, Per; Ortiz, Alberto; Ostrikov, Kostya; Otto, Siegmar; Outeiro, Tiago F.; Ouyang, Songying; Paganoni, Sabrina; Page, Andrew; Palm, Christoph; Paradies, Yin; Parsons, Michael H.; Parsons, Nick; Pascal, Pigny; Paul, Elisabeth; Peckham, Michelle; Pedemonte, Nicoletta; Pellizzon, Michael A.; Petrelli, M.; Pichugin, Alexander; Pinto, Carlos J. C.; Plevris, John N.; Pollesello, Piero; Polz, Martin; Ponti, Giovanna; Porcelli, Piero; Prince, Martin; Quinn, Gwendolyn P.; Quinn, Terence J.; Ramula, Satu; Rappsilber, Juri; Rehfeldt, Florian; Reiling, Jan H.; Remacle, Claire; Rezaei, Mohsen; Riddick, Eric W.; Ritter, Uwe; Roach, Neil W.; Roberts, David D.; Robles, Guillermo; Rodrigues, Tiago; Rodriguez, Cesar; Roislien, Jo; Roobol, Monique J.; Rowe, J. Alexandra; Ruepp, Andreas; Van Ruitenbeek, Jan; Rust, Petra; Saad, Sonia; Sack, George H.; Santos, Manuela; Saudemont, Aurore; Sava, Gianni; Schrading, Simone; Schramm, Alexander; Schreiber, Martin; Schuler, Sidney; Schymkowitz, Joost; Sczyrba, Alexander; Seib, Kate L.; Shi, Han-ping; Shimada, Tomohiro; Shin, Jeon-soo; Shortt, Colette; Silveyra, Patricia; Skinner, Debra; Small, Ian; Smeets, Paul A. M.; So, Po-wah; Solano, Francisco; Sonenshine, Daniel E.; Song, Jiangning; Southall, Tony; Speakman, John R.; Srinivasan, Mandyam V.; Stabile, Laura P.; Stasiak, Andrzej; Steadman, Kathryn J.; Stein, Nils; Stephens, Andrew W.; Stewart, Douglas I.; Stine, Keith; Storlazzi, Curt; Stoynova, Nataliya V.; Strzalka, Wojciech; Suarez, Oscar M.; Sultana, Taranum; Sumant, Anirudha V.; Summers, Mathew J.; Sun, Gang; Tacon, Paul; Tanaka, Kozo; Tang, Haixu; Tanino, Yoshinori; Targett-adams, Paul; Tayebi, Mourad; Tayyem, Reema; Tebbe, Christoph C.; Telfer, Evelyn E.; Tempel, Wolfram; Teodorczyk-injeyan, Julita A.; Thijs, Gert; Thorne, Sally; Thrift, Amanda G.; Tiffon, Celine; Tinnefeld, Philip; Tjahjono, Daryono H.; Tolle, Fabrice; Toth, Ervin; Del Tredici, Andria L.; Tsapas, Apostolos; Tsirigotis, Konstantinos; Turak, Ayse; Tzotzos, George; Udo, Edet E.; Utsumi, Toshiaki; Vaidyanathan, Subramanian; Vaillant, Michel; Valsesia, Armand; Vandenbroucke, Roosmarijn E.; Veiga, Feliciano H.; Vendrell, Marc; Vesk, Peter A.; Vickers, Paul; Victor, Victor M.; Villemur, Richard; Vohl, Marie-claude; Voolstra, Christian R.; Vuillemin, Anne; Wakelin, Steven; Waldron, Levi; Walsh, Laurence J.; Wang, Amanda Y.; Wang, Fuan; Wang, Yun; Watanabe, Yoichi; Weigert, Andreas; Wen, Jet-chau; Wham, Carol; White, Ethan P.; Wiener, Jan; Wilharm, Gottfried; Wilkinson, Simon; Willmann, Raffaella; Wilson, Coralie; Wirth, Brunhilde; Wojan, Timothy R.; Wolff, Mathieu; Wong, Bryan M.; Wu, Tzu-wei; Wuerbel, Hanno; Xiao, Xiangshu; Xu, Dong; Xu, J. W.; Xu, Jianping; Xue, Bin; Yalcin, Suayib; Yan, Hong; Yang, En-cheng; Yang, Shiqi; Yang, Wei; Ye, Yuzhen; Ye, Zhi-qiang; Yli-kauhaluoma, Jari; Yoneyama, Hiroshi; Yu, Ying; Yuan, Guo-cheng; Yuh, Chiou-hwa; Zaccolo, Manuela; Zeng, Chen; Zevnik, Branko; Zhang, Chi; Zhang, Li; Zhang, Li; Zhang, Yingkai; Zhang, Yusen; Zhang, Zhiyong; Zhang, Zhong-yin; Zhao, Yuan; Zhou, Min; Zuberbier, Torsten; Aanei, Carmen M.; Ahmad, Rafi; Al-lawama, Manar; Alanio, Alexandre; Allardyce, Judith; Alonso-caneiro, David; Atack, John M.; Baier, Dirk; Bansal, Abhisheka; Benezeth, Yannick; Berbesque, Colette; Berrevoet, Frederik; Biedermann, Peter H. W.; Bijleveld, Erik; Bittner, Florian; Blombach, Fabian; Van Den Bos, Wouter; Boudreau, Shellie A.; Bramoweth, Adam D.; Braubach, Oliver; Cai, Yufeng; Campbell, Matthew; Cao, Zanxia; Catry, Thibault; Chen, Xin; Cheng, Shuiqin; Chung, Hee-jung; Chavez-fumagalli, Miguel A.; Conway, Aaron; Costa, Bruno M.; Cyr, Normand; Dean, Lorraine T.; Denzel, Martin S.; Dlamini, S. V.; Dudley, Kevin J.; Dufies, Maeva; Ecke, Thorsten; Eckweiler, Denitsa; Eixarch, Elisenda; El-adawy, Hosny; Emmrich, Julius V.; Eustace, Alex J.; Falter-wagner, Christine M.; Fuss, Johannes; Gao, Jianzhao; Gill, Martin R.; Gloyn, Liz; Goggs, Robert; Govinden, Usha; Greene, Garrett; Greiff, Victor; Grundle, D. S.; Gruneberg, Patrick; Gumede, Nicksy; Haore, Gbaguidi; Harrison, Pille; Hoenner, Xavier; Hojsgaard, Diego; Hori, Hikaru; Ikonomopoulou, Maria P.; Jeurissen, Patrick; Johnson, Daniel M.; Kabra, Dhiraj; Kamagata, Koji; Karmakar, Chandan; Kasian, Olga; Kaye, Linda K.; Khan, Murad M.; Kim, Yong-min; Kish, J. K.; Kobold, Sebastian; Kohanbash, Gary; Kohls, Gregor; Kugler, Jan-michael; Kumar, Gyanendra; Lacy-colson, Jon; Latif, Asam; Lauschke, Volker M.; Li, Bingling; Lim, Chinten J.; Liu, Fang; Liu, Xiaodong; Lu, Jin-jian; Lu, Qiang; Mahavadi, Poornima; Marzocchi, Ugo; Mcgarrigle, Christine A.; Van Meerten, Tom; Min, Rogier; Moal, Iain; Molari, Massimiliano; Molleman, Lucas; Mondal, Saiful R.; Van De Mortel, Thea; Moss, W. N.; Moultos, Othonas A.; Mukherjee, Maheswari; Nakayama, Kazuhiko; Narayan, Edward; Navaratnarajah,; Neumann, Philipp-alexander; Nie, Jiyun; Nie, Yingjiu; Niemeyer, Frank; Fiona,; Nwaiwu, Ogueri; Oldenmenger, Wendy H.; Olumayede, Emmanuel; Ou, Jianhong; Pallebage-gamarallage, Menuka; Pearce, Simon P.; Pelkonen, Tuula; Pelleri, Maria C.; Pereira, Joana L.; Pheko, Mpho; Pinto, Karina A.; Piovesan, Allison; Pluess, Michael; Podolsky, Illya M.; Prescott, Julie; Qi, Dongchen; Qi, Xingshun; Raikou, Vaia D.; Ranft, Andreas; Rhodes, Johanna; Rotge, Jean-yves; Rowe, Anna D.; Saggar, Manish; Schuon, Robert A.; Shahid, Shaouli; Shalchyan, Vahid; Shirvalkar, Prasad; Shiryayev, Oleg; Singh, Jugpreet; Smout, Michael J.; Soares, Antonio; Song, Chunjiao; Srivastava, Kshitij; Srivastava, Rupesh K.; Sun, Jim; Szabo, Attila; Szymanski, Wiktor; Tai, Chan N. P.; Takeuchi, Hisashi; Tanadini-lang, S.; Tang, Fei; Tao, Wanyin; Theron, G.; Tian, Chang F.; Tian, Yu-shi; Tuttle, Lisa M.; Valenti, Anna; Verlot, Pierre; Walker, Mirella; Wang, Jun; Welter, Danielle; Winslade, Matthew; Wu, Dalei; Wu, Yi-rui; Xiao, Han; Xu, Beisi; Xu, Juan; Xu, Ziyue; Yang, Dongdong; Yang, Mingjun; Yankilevich, Patricio; You, Yuyi; Yu, Chenglong; Zhan, Jian; Zhang, Gong; Zhang, Kai; Zhang, Tuo; Zhang, Yi; Zhao, Guoyan; Zhao, Jing; Zhou, Xiaofan; Zhu, Zhenxing; Ajani, Penelope A.; Anazodo, Udunna C.; Bagloee, Saeed A.; Bail, Kasia; Bar, Ido; Bathelt, Joe; Benkeser, David; Bernier, Meghan L.; Blanchard, Adam M.; Boakye, Dominic W.; Bonatsos, Vasileios; Boon, Michele H.; Bouboulis, George; Bromfield, Elizabeth; Brown, Joshua; Bul, Kim C. M.; Burton, Kathryn J.; Butkowski, Eugene G.; Carroll, Grace; Chao, Fengqing; Charrier, Elisabeth E.; Chen, Xiaoyin; Chen, Yu-chih; Chenguang,; Choi, Jane R.; Christoffersen, Tore; Comel, Joao C.; Cosse, Cyril; Cui, Yanru; Van Dessel, Pieter; Dhaval,; Diodato, Daria; Duffey, Maelle; Dutt, Avik; Egea, Luis G.; El-said, Mohammed; Faye, Martin; Fernandez-fernandez, Beatriz; Foley, Kieran G.; Founou, Luria L.; Fu, Fan; Gadelkareem, Rabea A.; Galimov, Evgeny; Garip, Gulcan; Gemmill, Alison; Gouil, Quentin; Grey, James; Gridneva, Zoya; Grothe, Michel J.; Grebert, Theophile; Guerrero, Fabricio; Guignard, Leo; Haenssgen, Marco J.; Hasler, David; Holgate, Joan Y.; Huang, Ancheng; Hulse-kemp, Amanda M.; Jean-quartier, Claire; Jeon, Sang-min; Jia, Yangyang; Jutzeler, Catherine; Kalatzis, Panagiotis; Karim, Masud; Karsay, Kathrin; Keitel, Anne; Kempe, Andreas; Keown, Jeremy R.; Khoo, Chin M.; Khwaja, Nyil; Kievit, Rogier A.; Kosanic, Aleksandra; Koutoukidis, Dimitrios A.; Kramer, Paul; Kumar, Dilip; Kirag, Nukhet; Lanza, Giuseppe; Le, Thuc D.; Leem, Jung W.; Leightley, Daniel; Leite, Andreia; Lercher, Lukas; Li, Ying; Lim, Renly; Lima, Luiz R. A.; Lin, Li; Ling, Tong; Liu, Yuchen; Liu, Zhonghua; Lu, Yao; Lum, Fok M.; Luo, Hang; Machhi, Jatin; Macleod, Angus; Macwan, Isaac; Madala, Hanumantha R.; Madani, Nima; De Maio, Nicola; Makowiecki, Kalina; Mallinson, Daniel J.; Margelyte, Ruta; Maria, Caracausi; Markonis, Y.; Marsili, Luca; Mavoa, Suzanne; Mcwilliams, Lorna; Megersa, Moa; Mendes, Caetano S. M.; Menichetti, Julia; Mercieca-bebber, Rebecca; Miller, Jack J.; Minde, David-paul M.; Minges, Alexander; Mishra, Eleanor; Mishra, Virendra R.; Moores, Carly; Morrice, Nicola; Moskalensky, Alexander E.; Navarin, Nicolo; Negera, Edessa; Nolet, Philippe; Nordberg, Ana; Norden, Rickard; Nowicki, Jessica P.; Olova, Nelly; Olszewski, Pawel; Onzima, Robert; Pan, Chih-long; Park, Charny; Park, Dong Ik; Park, Seyoung; Patil, Chandrashekhar D.; Pedro, Sansoa A.; Perry, Samuel R.; Peter, Jessica; Peterson, Brent M.; Pezzuolo, Andrea; Pozdnyakov, Ilya; Qian, Siyu; Qin, Lei; Rafe, Ali; Raote, Ishier; Raza, Ali; Rebl, Henrike; Refai, Osama; Regan, Tim; Richa, Tambi; Richardson, Mark F.; Robinson, K. R.; Rossoni, Luca; Rouet, Romain; Safaei, Soroush; Schneeberger, Pierre H. H.; Schwotzer, Daniela; Sebastian, Agata; Selinski, Jennifer; Seltmann, Stefanie; Sha, Feng; Shalev, Nir; Shang, Jin-long; Singer, Josef; Singh, Mandeep; Smith, Taylor; Solomon-moore, Emma; Song, Lijuan; Soraggi, Samuele; Stanley, Ryan; Steckhan, Nico; Strobl, Frederic; Subissi, Lorenzo; Supriyanto, Irwan; Surve, Chinmay R.; Suzuki, Tomo; Syme, Caitlin; Sorelius, Karl; Tang, Young; Tantawy, Marwa; Tennakoon, Sumudu; Teseo, Serafino; Toelzer, Christine; Tomov, Nikola; Tovar, Miguel; Tran, Linh; Tripathi, Sushil; Tuladhar, Anil M.; Ukubuiwe, Azubuike C.; Ung, Carolina O. L.; Valgepea, Kaspar; Vatanparast, Hamid; Vidal, Arnau; Wang, Fang; Wang, Qing; Watari, Ricky; Webster, Rebecca; Webster, Ruth; Wei, Junnian; Wibowo, David; Wingenbach, Tanja S. H.; Xavier, Rose M.; Xiao, Shumin; Xiong, Peng; Xu, Shicai; Xu, Shilin; Yao, Ruifeng; Yao, Wen; Yin, Qinan; Yu, Yongbo; Zaitsu, Masayoshi; Zeineb, Zian; Zhan, Xiao-yong; Zhang, Jilei; Zhang, Rongqiang; Zhang, Wei; Zhang, Xianglilan; Zheng, Shan; Zhou, Bailing; Zhou, Xiaoyan; Ahmad, Haroon; Akinwumi, Sayo A.; Albery, Gregory F.; Alhowimel, Ahmed; Ali, Junaid; Alshehri, Mansour; Alsuhaibani, Mohammed; Anikin, Andrey; Azubuike, Samuel O.; Bach-mortensen, Anders; Baltiansky, Lior; Bartas, Martin; Belachew, Kiflemariam Y.; Bhardwaj, Vivek; Binder, Karin; Bland, Nicholas S.; Boah, Michael; Bullen, Benjamin; Calabro, Giovanna E.; Callahan, Tiffany J.; Cao, Bing; Chalmers, Kelsey; Chang, Wei; Che, Zhengping; Chen, Andrew T. Y.; Chen, Haimin; Chen, Huaming; Chen, Youning; Chen, Zhao; Choi, Youngrok; Chowdhury, Mohiuddin A. K.; Christensen, Martin R.; Cooke, Robert S. C.; Cottini, Marzia; Covington, Natalie V.; Cunningham, Catriona; Delarocque, Julien; Devos, Lucie; Dhar, Aurup R.; Ding, Ke-feng; Dong, Kexian; Dong, Zheng; Dreyer, Niklas; Ekstrand, Chelsea; Fardet, Tanguy; Feleke, Berhanu E.; Feurer, Thomas; Freitas, Angela; Gao, Tian; Asefa, N. G.; Giganti, Francesco; Grabowski, Piotr; Guerra-mora, Jose R.; Guo, Chengying; Guo, Xinyi; Gupta, Himanshu; He, Shuonan; Heijne, Marloes; Heinemann, Stephanie; Hogrebe, Alexander; Huang, Zhengping; Iskander-rizk, Sophinese; Iyer, Lavanya M.; Jahan, Yasmin; James, Ameh S.; Joel, Emmanuel; Joffroy, Bastian; Jegousse, Clara; Kambondo, George; Karnati, Priyanka; Kaya, Cihan; Ke, An; Kelly, Daniel; Kickert, Rob; Kidibule, Peter E.; Kieselmann, Jennifer P.; Kim, Hyeon J.; Kitazawa, Takeshi; Lamberts, Aniek; Li, You; Liang, Huakang; Linn, Sabrina N.; Litfin, Thomas; Liusuo, Wang; Lygirou, Vasiliki; Mahato, Ajay K.; Mai, Zhi-ming; Major, Rupert W.; Mali, Samira; Mallis, Panagiotis; Mao, Wenzhi; Mao, Wenzhi; Marvin-dowle, Katie; Marvin-dowle, Katie; Mason, Leanda D.; Merideth, Ben; Merino-plaza, Maria J.; Merlaen, Britt; Messina, Rossella; Mishra, Anand K.; Muhammad, Junaid; Musinguzi, Conrad; Nanou, Afroditi; Naqash, Amreen; Nguyen, Joe T.; Nguyen, Thi T. H.; Ni, Duan; Nida,; Notcovich, Shirli; Ohst, Barnabas; Ollivier, Quinn R.; Osses, Daniel F.; Peng, Xiangda; Plantinga, Arnoud; Pulia, Michael; Rafiq, Muhammad; Raman, Ayush; Raucher-chene, Delphine; Rawski, Rafal; Ray, Asit; Razak, Lubna A.; Rudolf, Kevin; Rusch, Peter; Sadoine, Margaux L.; Schmidt, Axel; Schurr, Roey; Searles, Stephen; Sharma, Saurab; Sheehan, Barry; Shi, Chunhu; Shohayeb, Belal; Sommerlad, Andrew; Strehlow, Jan; Sun, Xianbao; Sundar, Raghav; Taherzadeh, Ghazaleh; Tahir, Nur D. M.; Tang, Jun; Testa, Jean; Tian, Zhiqi; Tingting, Qian; Verheijen, Geert P.; Vickstrom, Casey; Wang, Teng; Wang, Xiaomin; Wang, Zhenxing; Wei, Pan; Wilson, Alex; Wyart,; Yassine, Abdul-amir; Yousefzadeh, Abbas; Zare, Asma; Zeng, Zhen; Zhang, Chengrong; Zhang, Haowen; Zhang, Linxing; Zhang, Tongchuan; Zhang, Weijia; Zhang, Zhe; Zhou, Jianyu; Zhu, Dongjie; Adamo, Vincenzo; Adeyemo, Adebolajo A.; Aggelidou, Maria; Al-owaifeer, Adi M.; Al-riyami, Arwa Z.; Alzghari, Saeed K.; Andersen, Vibeke; Angus, Kathryn; Asaduzzaman, Muhammad; Asady, Hadi; Ato, Dai; Bai, Xiaoyong; Baines, Rebecca L.; Ballantyne, Maghan; Ban, Bo; Beck, Jill; Ben-nafa, Walid; Black, Emma; Blancher, Antoine; Blankstein, Ron; Bodagh, Neil; Borges, Paulo A. V.; Brooks, Anastasia; Brox-ponce, Josue; Brunetti, Arturo; Canham, Colin D.; Carninci, Piero; Carvajal, Richard; Chang, Shun C.; Chao, Jie; Chatterjee, Pranab; Chen, He; Chen, Yi-chun; Chhatriwalla, Adnan K.; Chikowe, Ibrahim; Chuang, Trees-juen; Collevatti, Rosane G.; Valera-cornejo, Diego A.; Cuenda, Ana; Dao, Myriam; Dauga, Delphine; Deng, Zaian; Devkota, Kiran; Doan, Lisa V.; Elewa, Yaser H. A.; Fan, Dongsheng; Faruk, Mohammed; Feifei, Shi; Ferguson, Trevor S.; Fleres, Francesco; Foster, Emma J.; Foster, C. Stephen; Furer, Tzvi; Gao, Yibo; Garcia-rivera, Enid J.; Gazdar, Adi; George, Ronald B.; Ghosh, Sayantan; Gianchecchi, Elena; Gleason, Joshua M.; Hackshaw, Allan; Hall, Adam; Hall, Richard; Harper, Paul; Hogg, William E.; Huang, Guangqun; Hunter, Kylie E.; Ijzerman, Adriaan P.; Jesus, Carlos; Jian, Gao; Lewis, James S., Jr.; Kanj, Souha S.; Kaur, Harsheen; Kelly, Shona; Kheir, Fayez; Kichatova, V. S.; Kiyani, Musa; Klein, Reinhild; Kovesi, Tom; Kraschnewski, Jennifer L.; Kumar, Addanki P.; Labutin, Dmitry; Lazo-langner, Alejandro; Leclercq, Guy; Li, Maoteng; Li, Qingchun; Li, Tangliang; Li, Yongzhe; Liao, Wei-ting; Liao, Zheng-yin; Lin, Jessica; Lizer, J.; Lobreglio, Giambattista; Lowies, Cher; Lu, Cheng; Majeed, Haroon; Martin, Adam; Martinez-sobrido, Luis; Meresh, Edwin; Middelveen, Marianne; Mohebbi, Alireza; Mota, Jorge; Mozaheb, Zahra; Muyaya, Ley; Nandhakumar, Amar; Ng, Sheryl H. X.; Obeidat, Monther; Oh, Deog-hwan; Owais, Mohammed; Pace-asciak, Pia; Panwar, Ajay; Park, Caroline; Patterson, Chris; Penagos-tabaree, Felipe; Pianosi, Paolo T.; Pinzi, Valentina; Pridans, Clare; Psaroulaki, Anna; Pujala, Ravi Kumar; Pulido-arjona, Leonardo; Qi, Peng-fei; Rahman, Proton; Rai, Nayanjot K.; Rassaf, Tienush; Refardt, Julie; Ricciardi, Walter; Riess, Olaf; Rovas, Alexandros; Sacks, Frank M.; Saleh, Sherif; Sampson, Christopher; Schmutz, Axel; Sepanski, Robert; Sharma, Neeraj; Singh, Manisha; Spearman, Paul; Subramaniapillai, Mehala; Swali, Ritu; Tan, Cher M.; Tellechea, Juan I.; Thomas, Lisa-marie; Tong, Xin; Veys, Ralf; Vitriol, Veronica; Wang, Horng-dar; Wang, Jinhui; Wang, Jiucun; Waugh, Jason; Webb, S. A.; Williams, Brendan A.; Workman, Alan D.; Xiang, Tingxiu; Xie, Li-xin; Xu, Jun; Xu, Taosheng; Yang, Chongjun; Yoon, Jihoon G.; Yuan, Christina M.; Zaritsky, Arno; Zhang, Yao; Zhao, Haochen; Zuckerman, Hannah; Lyu, Ran; Pullan, Wayne; Zhou, Yaoqi. |
Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of a large offline gold-standard benchmark of relevant documents that cover a variety of research fields such that newly developed literature search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we have established the RElevant LIterature SearcH consortium consisting of more than 1500 scientists from 84 countries, who have collectively annotated the relevance of over 180 000 PubMed-listed articles with regard to their respective seed (input) article/s. The majority of annotations were contributed by highly experienced, original authors of the seed articles.... |
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Ano: 2019 |
URL: https://archimer.ifremer.fr/doc/00659/77117/78538.pdf |
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Massana, Ramon; Gobet, Angelique; Audic, Stephane; Bass, David; Bittner, Lucie; Boutte, Christophe; Chambouvet, Aurelie; Christen, Richard; Claverie, Jean-michel; Decelle, Johan; Dolan, John R.; Dunthorn, Micah; Edvardsen, Bente; Forn, Irene; Forster, Dominik; Guillou, Laure; Jaillon, Olivier; Kooistra, Wiebe H. C. F.; Logares, Ramiro; Mahe, Frederic; Not, Fabrice; Ogata, Hiroyuki; Pawlowski, Jan; Pernice, Massimo C.; Probert, Ian; Romac, Sarah; Richards, Thomas; Santini, Sebastien; Shalchian-tabrizi, Kamran; Siano, Raffaele; Simon, Nathalie; Stoeck, Thorsten; Vaulot, Daniel; Zingone, Adriana; De Vargas, Colomban. |
Although protists are critical components of marine ecosystems, they are still poorly characterized. Here we analysed the taxonomic diversity of planktonic and benthic protist communities collected in six distant European coastal sites. Environmental deoxyribonucleic acid (DNA) and ribonucleic acid (RNA) from three size fractions (pico-, nano- and micro/mesoplankton), as well as from dissolved DNA and surface sediments were used as templates for tag pyrosequencing of the V4 region of the 18S ribosomal DNA. Beta-diversity analyses split the protist community structure into three main clusters: picoplankton-nanoplankton-dissolved DNA, micro/mesoplankton and sediments. Within each cluster, protist communities from the same site and time clustered together,... |
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Ano: 2015 |
URL: http://archimer.ifremer.fr/doc/00275/38594/37190.pdf |
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Gobet, Angelique; Quince, Christopher; Ramette, Alban. |
High-throughput sequencing techniques are becoming attractive to molecular biologists and ecologists as they provide a time- and cost-effective way to explore diversity patterns in environmental samples at an unprecedented resolution. An issue common to many studies is the definition of what fractions of a data set should be considered as rare or dominant. Yet this question has neither been satisfactorily addressed, nor is the impact of such definition on data set structure and interpretation been fully evaluated. Here we propose a strategy, MultiCoLA (Multivariate Cutoff Level Analysis), to systematically assess the impact of various abundance or rarity cutoff levels on the resulting data set structure and on the consistency of the further ecological... |
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Ano: 2010 |
URL: https://archimer.ifremer.fr/doc/00488/59949/63199.pdf |
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Logares, Ramiro; Audic, Stephane; Bass, David; Bittner, Lucie; Boutte, Christophe; Christen, Richard; Claverie, Jean-michel; Decelle, Johan; Dolan, John R.; Dunthorn, Micah; Edvardsen, Bente; Gobet, Angelique; Kooistra, Wiebe H. C. F.; Mahe, Frederic; Not, Fabrice; Ogata, Hiroyuki; Pawlowski, Jan; Pernice, Massimo C.; Romac, Sarah; Shalchian-tabrizi, Kamran; Simon, Nathalie; Stoeck, Thorsten; Santini, Sebastien; Siano, Raffaele; Wincker, Patrick; Zingone, Adriana; Richards, Thomas A.; De Vargas, Colomban; Massana, Ramon. |
Background Biological communities are normally composed of a few abundant and many rare species. This pattern is particularly prominent in microbial communities, in which most constituent taxa are usually extremely rare. Although abundant and rare subcommunities may present intrinsic characteristics that could be crucial for understanding community dynamics and ecosystem functioning, microbiologists normally do not differentiate between them. Here, we investigate abundant and rare subcommunities of marine microbial eukaryotes, a crucial group of organisms that remains among the least-explored biodiversity components of the biosphere. We surveyed surface waters of six separate coastal locations in Europe, independently considering the picoplankton,... |
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Ano: 2014 |
URL: http://archimer.ifremer.fr/doc/00186/29683/28098.pdf |
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Le Gall, F.; Rigaut-jalabert, F.; Marie, D.; Garczarek, L.; Viprey, M.; Gobet, Angelique; Vaulot, D.. |
In late 2004, the BIOSOPE cruise sailed between the equatorial influenced waters off the Marquesas Islands and the nutrient enriched waters of the Chilean upwelling. Along the way, it explored the Southeast Pacific gyre centred around Easter Island, which is probably the most oligotrophic oceanic region on earth. During this cruise, we undertook a vigorous effort to isolate novel photosynthetic picoplanktonic eukaryotes. Two strategies were attempted on board: enrichment of filtered samples with culture medium and sorting of specific populations by flow cytometry based on size and chlorophyll fluorescence. Over 1900 pre-cultures were started and then further purified by flow cytometry, serial dilution or pipette isolation to yield a total of 212 strains.... |
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Ano: 2008 |
URL: https://archimer.ifremer.fr/doc/00489/60073/63392.pdf |
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Gobet, Angelique; Mest, Laetitia; Perennou, Morgan; Dittami, Simon M.; Caralp, Claire; Coulombet, Celine; Huchette, Sylvain; Roussel, Sabine; Michel, Gurvan; Leblanc, Catherine. |
Background: Holobionts have a digestive microbiota with catabolic abilities allowing the degradation of complex dietary compounds for the host. In terrestrial herbivores, the digestive microbiota is known to degrade complex polysaccharides from land plants while in marine herbivores, the digestive microbiota is poorly characterized. Most of the latter are generalists and consume red, green, and brown macroalgae, three distinct lineages characterized by a specific composition in complex polysaccharides, which represent half of their biomass. Subsequently, each macroalga features a specific epiphytic microbiota, and the digestive microbiota of marine herbivores is expected to vary with a monospecific algal diet. We investigated the effect of four... |
Tipo: Text |
Palavras-chave: Microbe-host interactions; Digestive microbiota; Abalone; Macroalgae; Holobiont. |
Ano: 2018 |
URL: https://archimer.ifremer.fr/doc/00489/60071/63368.pdf |
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Perez-pascual, David; Lunazzi, Aurelie; Magdelenat, Ghislaine; Rouy, Zoe; Roulet, Alain; Lopez-roques, Celine; Larocque, Robert; Barbeyron, Tristan; Gobet, Angelique; Michel, Gurvan; Bernardet, Jean-francois; Duchaud, Eric. |
Tenacibaculum maritimum is a devastating bacterial pathogen of wild and farmed marine fish with a broad host range and a worldwide distribution. We report here the complete genome sequence of the T. maritimum type strain NCIMB 2154(T). The genome consists of a 3,435,971-base pair circular chromosome with 2,866 predicted protein-coding genes. Genes encoding the biosynthesis of exopolysaccharides, the type IX secretion system, iron uptake systems, adhesins, hemolysins, proteases, and glycoside hydrolases were identified. They are likely involved in the virulence process including immune escape, invasion, colonization, destruction of host tissues, and nutrient scavenging. Among the predicted virulence factors, type IX secretion-mediated and cell-surface... |
Tipo: Text |
Palavras-chave: Tenacibaculum maritimum; Fish pathogen; Virulence factors; Genome; Toxins. |
Ano: 2017 |
URL: https://archimer.ifremer.fr/doc/00488/59939/63150.pdf |
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Jousset, Alexandre; Bienhold, Christina; Chatzinotas, Antonis; Gallien, Laure; Gobet, Angelique; Kurm, Viola; Kuesel, Kirsten; Rillig, Matthias C.; Rivett, Damian W.; Salles, Joana F.; Van Der Heijden, Marcel G. A.; Youssef, Noha H.; Zhang, Xiaowei; Wei, Zhong; Hol, W. H. Gera. |
Rare species are increasingly recognized as crucial, yet vulnerable components of Earth's ecosystems. This is also true for microbial communities, which are typically composed of a high number of relatively rare species. Recent studies have demonstrated that rare species can have an over-proportional role in biogeochemical cycles and may be a hidden driver of microbiome function. In this review, we provide an ecological overview of the rare microbial biosphere, including causes of rarity and the impacts of rare species on ecosystem functioning. We discuss how rare species can have a preponderant role for local biodiversity and species turnover with rarity potentially bound to phylogenetically conserved features. Rare microbes may therefore be overlooked... |
Tipo: Text |
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Ano: 2017 |
URL: https://archimer.ifremer.fr/doc/00488/59940/63159.pdf |
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Registros recuperados: 16 | |
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